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Andrew T Bender Selected Research

evobrutinib

1/2020Safety, Tolerability, Pharmacokinetics, Target Occupancy, and Concentration-QT Analysis of the Novel BTK Inhibitor Evobrutinib in Healthy Volunteers.
12/2019Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
1/2019Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.

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Andrew T Bender Research Topics

Disease

6Autoimmune Diseases (Autoimmune Disease)
01/2021 - 03/2016
5Communicable Diseases (Infectious Diseases)
01/2022 - 01/2018
3Rheumatoid Arthritis
12/2019 - 01/2013
3Arthritis (Polyarthritis)
03/2016 - 01/2013
2Systemic Lupus Erythematosus (Libman-Sacks Disease)
12/2019 - 01/2019
2Nephritis
03/2016 - 06/2014
1COVID-19
04/2021
1Human Influenza (Influenza)
04/2021
1Infections
01/2020
1Immune System Diseases (Immune Disorders)
12/2019
1Neoplasms (Cancer)
12/2019
1Multiple Sclerosis
12/2019
1Virus Diseases (Viral Diseases)
01/2018
1Proteinuria
06/2014
1Asthma (Bronchial Asthma)
12/2009
1Atherosclerosis
04/2007
1Erectile Dysfunction
09/2006
1Pathologic Processes
11/2004

Drug/Important Bio-Agent (IBA)

5Nucleic AcidsIBA
01/2022 - 01/2018
4Agammaglobulinaemia Tyrosine KinaseIBA
01/2020 - 03/2016
3Fc Receptors (Fc Receptor)IBA
01/2020 - 03/2016
3evobrutinibIBA
01/2020 - 01/2019
3Pharmaceutical PreparationsIBA
01/2020 - 09/2006
2pristane (pristan)IBA
03/2016 - 06/2014
2AutoantibodiesIBA
03/2016 - 06/2014
1N-acetyltalosaminuronic acid (NAT)IBA
04/2021
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2021
1Antiviral Agents (Antivirals)IBA
01/2020
1ibrutinibIBA
12/2019
1InterferonsIBA
06/2014
1Interferon Type IIBA
06/2014
1CollagenIBA
01/2013
1LuminolIBA
01/2013
1Biomarkers (Surrogate Marker)IBA
01/2013
1ChemokinesIBA
12/2009
1Fatty Acids (Saturated Fatty Acids)IBA
04/2007
1Rosiglitazone (Avandia)FDA Link
04/2007
1Biological ProductsIBA
04/2007
1Insulin (Novolin)FDA Link
04/2007
1Sildenafil Citrate (Viagra)FDA Link
09/2006
1EnzymesIBA
09/2006
1Tadalafil (Cialis)FDA Link
09/2006
1Vardenafil Dihydrochloride (Levitra)FDA Link
09/2006
1diethylstilbestrol monophosphate (PDES)IBA
11/2004

Therapy/Procedure

1Art Therapy
01/2020